COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 176
● Dr. Zachary: p.2353248 (B vitamins)
● Sodano: RBC B12 references or Ch.4 for electrolytes if
relevant
● Weatherby & Ferguson: B12/folate in Blood Chem
Additional Resources:
● Introduction to Micronutrient Testing
Vitamin B1
Thiamine (Vitamin B1) plays a central role in energy metabolism,
neurological function, and cardiovascular vitality. As a coenzyme,
it is essential for the conversion of nutrients into energy and the
synthesis of DNA.
Deficiencies can be assessed through red blood cell (RBC)
transketolase activity, a highly specific but costly marker, since this
enzyme depends entirely on thiamine for its function.
In practice, clinicians may first look for indirect signs: a widened
anion gap, low CO2 levels, and subtly low-normal hematocrit
(HCT) and hemoglobin (HGB) values.
Beriberi4thiamine deficiency's most well-known
expression4comes in four forms: dry, wet, cerebral, and
gastrointestinal. Each presents uniquely, reflecting thiamine’s
diverse physiological roles.
Vitamin B1
Range
Units - Male
Conventional
2.2-107.3 nmol/L
Optimal / Functional
2.2-107.3 nmol/L
Anion Gap Test
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