COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 222
● Environmental modifications to reduce workplace stressors
● Regular moderate exercise focusing on activities with a
mindfulness component
Outcome: The patient experienced gradual improvement over 2-3
months. Panic attacks decreased in frequency from several times
weekly to less than once per month. Sleep quality improved
substantially, which contributed to better cognitive function. The
patient was able to develop more effective workplace
boundaries and improve executive function, resulting in better job
performance despite working fewer hours [49].
Case Study 3: APOE and Cognitive Decline
Patient Profile:
● 68-year-old male
● Early signs of cognitive decline
● Family history of Alzheimer's disease
● Slightly elevated cholesterol
● Overweight with mild hypertension
Genetic Testing Results:
● APOE ε4/ε3 (heterozygous for APOE4)
● MTHFR C677T (+/-) heterozygous
Intervention Approach: After genetic testing revealed the
presence of an APOE ε4 allele, the practitioner implemented a
brain-protective protocol:
● Mediterranean diet with emphasis on olive oil, fatty fish, and
plant foods
● Time-restricted eating with a 14-16 hour overnight fast
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