COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 236
[70] Dr. Hagmeyer. "The Genetics Of Histamine Intolerance.
Understanding DAO & HNMT Enzyme SNPs." November 5, 2024.
https://www.drhagmeyer.com/genetics-of-histamine-intolerance/
[71] Wikipedia. "Experiments involving Hnmt-knockout mice have
shown that a deficiency in HNMT leads to increased brain
histamine concentrations." January 23, 2025.
https://en.wikipedia.org/wiki/Histamine_N-methyltransferase
Liver, Renal, & Gi Health
Liver & Detox Markers
AST, ALT, ALP, GGT, bilirubin, albumin/globulin ratio, phase I/II
detox context.
Required Reading:
● Sodano: Chapter 3 (Liver, GB, Pancreas)
● Dr. Zachary: p.27382 (CMP coverage), especially AST/ALT,
etc.
● Weatherby & Ferguson: Liver enzymes in Blood Chem
The liver is responsible for over 500 essential functions, and one of
its most important jobs is detoxification4filtering and breaking
down substances from the blood to protect the body and support
overall health. Everything absorbed from the digestive tract passes
through the liver first, where toxins, drugs, and waste products are
processed before they reach the rest of the body.
Detoxification happens in two main phases.
Phase I:
First, the liver uses a group of specialized enzymes to begin
breaking down harmful substances. This process can sometimes
turn toxins into more reactive forms, but it also prepares them for
the next step.
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