COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 296
○ P450 Enzyme System: Many herbs affect this
detoxification pathway, potentially altering medication
metabolism
Specific Botanical Contraindications
1. Artemisia Species (Wormwood):
○ Contraindicated in pregnancy (uterine stimulant)
○ May lower seizure threshold in epilepsy
○ Contains thujone, which can be neurotoxic at high
doses
○ May interact with anticonvulsant medications
2. Black Walnut:
○ High tannin content may cause liver stress with
prolonged use
○ Can irritate the gastrointestinal tract in sensitive
individuals
○ May interfere with nutrient absorption if used long-term
○ Contraindicated in tree nut allergies
3. Berberine-Containing Herbs:
○ May displace bilirubin, avoid in jaundiced infants
○ Can interfere with certain antibiotics
○ May affect blood glucose levels
○ Contraindicated in pregnancy
○ May exacerbate autoimmune conditions in some
individuals
4. Clove:
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