COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 379
approximately 70 tons of food during an average lifetime while
preventing harmful substances from entering circulation [1, 6].
Multicomponent Protective System
A sophisticated defense network including mucus layers, epithelial
cells, tight junctions, and immune components that work together
to maintain selective permeability
Critical Tight Junction Regulation
Dynamic protein structures between cells that open and close in
response to dietary factors, stress hormones, inflammatory
cytokines, and microbial interactions
Immune Surveillance Function
Specialized gut-associated lymphoid tissue that samples intestinal
contents while preventing inappropriate immune activation
against food and beneficial microbes
Microbiome Interactions
Trillions of beneficial microorganisms that influence barrier integrity
through metabolites and signaling molecules essential for gut
health
Cyrex Array 2: Intestinal Antigenic Permeability Screen™
The Array 2 test revolutionizes gut permeability assessment by
examining immune reactivity to specific proteins associated with
barrier breakdown, providing unprecedented insight into intestinal
health [6, 7].
Beyond Traditional Permeability Tests
Unlike lactulose/mannitol tests that only detect current leakage,
Array 2 identifies immunological consequences of barrier breach
that persist long after initial damage
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