COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 387
Detection of intestinal permeability before blood-brain barrier
compromise allows preventive strategies for neurological
protection
Differential Diagnosis Enhancement
Helps distinguish between primary gut-driven versus primary
brain-driven symptom patterns in complex presentations
Targeted Protocol Development
Enables precision intervention based on whether one or both
barriers show immune reactivity patterns
Clinical Decision Support
Guides appropriate timing and intensity of brain-supportive
therapies based on blood-brain barrier status
Treatment Response Monitoring
Allows objective reassessment of barrier function following
interventions to confirm improvement and guide protocol
adjustments
Conclusion: A New Paradigm for Chronic Disease Prevention
The Array 2 and Array 20 tests together represent a paradigm shift
in understanding the progression from barrier dysfunction to
chronic disease, offering a window into these processes before
significant tissue damage occurs [21, 22].
Early Detection Framework
Identification of barrier-specific immune reactivity often years
before clinically diagnosable conditions manifest
Preventive Intervention Model
Opportunity to address fundamental barrier dysfunction rather
than merely managing symptoms of established disease
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