COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 393
Cyrex Array 3X: Wheat/Gluten Proteome Reactivity &
Autoimmunity
Comprehensive Assessment of Gluten-Related Immune Reactions
Array 3X represents a significant advancement in gluten sensitivity
testing by examining immune reactivity against multiple
components of wheat and gluten proteins, rather than just one or
two basic markers [4]. This expanded panel evaluates antibody
reactions against various wheat proteins, peptides, and enzymes
involved in gluten metabolism and breakdown [5].
What Array 3X Evaluates
Array 3X measures antibodies (IgA and IgG) against the following
targets:
Wheat/Gluten Proteins and Peptides
Wheat IgG
Measures overall immune reaction to wheat proteins
Wheat IgA
Indicates mucosal immune activation against wheat
Native + Deamidated Alpha-Gliadin-33-mer
This peptide is highly resistant to digestion and has been identified
as particularly immunogenic in celiac disease [6]
Alpha-Gliadin-17-mer
Another immunogenic fragment of alpha-gliadin
Gamma-Gliadin-15-mer
A peptide from gamma-gliadin that can trigger immune reactions
Omega-Gliadin-17-mer
393
