COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 394
Derived from omega-gliadin, another potentially reactive
component
Glutenin-21-mer
From glutenin, the second major protein fraction in gluten
Gluteomorphin+Prodynorphin
Opioid-like peptides derived from gluten that may affect
neurological function [7]
Wheat Germ Agglutinin (WGA)
A lectin in wheat that can damage intestinal epithelium and
increase intestinal permeability [8]
Transglutaminase Enzymes
Transglutaminase-2
The classic enzyme targeted in celiac disease
Transglutaminase-3
Associated with skin manifestations of gluten sensitivity, including
dermatitis herpetiformis [9]
Transglutaminase-6
Linked to neurological manifestations of gluten sensitivity, including
ataxia and neuropathy [10]
Gliadin-Transglutaminase Complex
This compound represents the interaction between gliadin and
transglutaminase, which creates novel epitopes that can trigger
more severe autoimmune reactions [11]
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