COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 412
Stomach cells that produce intrinsic factor; parietal cell antibodies
are associated with pernicious anemia and autoimmune gastritis
Adrenal Antigens
Components of adrenal tissue; antibodies are linked to Addison's
disease and adrenal insufficiency
Osteocyte Antigens
Bone cell components; antibodies are associated with bone
density issues and osteoimmunity
Clinical Significance of Array 5
The expanded testing provided by Array 5 offers several critical
advantages over conventional autoimmune testing:
Early Detection of Autoimmune Processes
Research has consistently demonstrated that autoantibodies
appear in the bloodstream years before clinical symptoms
develop [7]. A landmark study published in the New England
Journal of Medicine showed that in systemic lupus erythematosus
(SLE), autoantibodies were present up to 9.4 years before
diagnosis, with a progressive accumulation of different antibodies
as the disease developed [8].
This pattern of early antibody development followed by gradual
symptom emergence has been documented across multiple
autoimmune conditions:
Tissue-Specific Autoimmunity Patterns
The pattern of antibodies identified on Array 5 can provide
valuable information about which tissues are being targeted and
which autoimmune conditions may be developing:
Thyroid Autoimmunity
412