COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 415
include fatigue, brain fog, joint pain, skin issues, digestive
problems, and low-grade inflammation. Array 5 can help identify
whether these symptoms may have an autoimmune basis, even
when standard diagnostic criteria are not yet met [19].
Established Autoimmune Disease
Patients with one diagnosed autoimmune condition have a
significantly increased risk of developing additional autoimmune
diseases. Array 5 can help monitor for the emergence of new
autoimmune targets in these high-risk individuals [20].
Intestinal Permeability
Research has established a strong connection between increased
intestinal permeability (leaky gut) and autoimmune disease
development. Patients with confirmed intestinal permeability on
Cyrex Array 2 may benefit from Array 5 screening to identify
whether this barrier dysfunction has allowed autoimmune
processes to begin [21].
Unexplained Inflammatory Symptoms
Patients with persistent inflammatory markers or symptoms that
don't fit a clear diagnostic pattern may have early-stage
autoimmunity that can be identified through Array 5 testing before
it progresses to diagnosable disease [22].
Conditions Where Array 5 is Especially Valuable
Array 5 is particularly useful for early detection and monitoring of
numerous autoimmune conditions:
Thyroid Autoimmunity
Hashimoto's thyroiditis and Graves' disease are among the most
common autoimmune conditions, affecting an estimated 5% of
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