COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 434
What distinguishes Array 7X from the standard Array 7 is the
inclusion of IgM antibody testing alongside IgG and IgA, creating
a full-spectrum view of both early and ongoing neuroimmune
responses [5].
This expanded assessment provides a more comprehensive
picture of immune reactivity in the pathogenesis of
neuro-inflammatory, neuro-autoimmune, and neurodegenerative
disorders [6].
The Clinical Significance of IgM Testing
The addition of IgM antibody testing in Array 7X represents a
significant advancement in early detection capabilities. IgM
antibodies are typically the first antibody class produced in
response to an antigen and may indicate a more acute, active
immune attack [7]. This makes IgM antibodies particularly valuable
for:
● Early detection of neuro-autoimmune reactivity before
chronic damage occurs [8]
● Identification of multi-focal motor neuropathy and lower
motor neuron syndromes [9]
● Monitoring early development of relapses in multiple sclerosis
[10]
● Early detection of chronic inflammatory demyelinating
polyneuropathy [11]
● Assessment of treatment effectiveness in related protocols
[12]
The presence of IgM antibodies often precedes the development
of IgG antibodies, which represent a more chronic, established
immune response. By detecting this earlier phase of the immune
response, Array 7X provides a critical opportunity for intervention
before significant tissue damage occurs [13].
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