COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 435
Neural Targets Assessed by Array 7X
Array 7X evaluates immune reactivity to several critical
neurological structures, each playing vital roles in brain, spinal
cord, and peripheral nerve health:
Myelin Basic Protein (MBP)
Myelin Basic Protein is a key structural component of the myelin
sheath that insulates nerve fibers and ensures proper nerve signal
conduction [14]. Antibodies targeting MBP have been implicated
in:
● Multiple sclerosis and other demyelinating conditions [15]
● Certain cases of autism spectrum disorders [16]
● Neurodegenerative conditions with white matter involvement
[17]
● Post-infectious encephalomyelitis [18]
MBP autoantibodies indicate disruption of the myelin sheath,
which can lead to impaired nerve signal transmission and
neurological dysfunction [19].
Gangliosides (GM1, GD1a, GD1b, GQ1b)
Gangliosides are complex glycosphingolipids that are highly
concentrated in neuronal cell membranes, particularly at
synapses [20]. They play crucial roles in:
● Cell recognition and signaling [21]
● Regulation of receptor function [22]
● Neuronal plasticity [23]
● Axonal stability and regeneration [24]
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