COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 536
immune system to attack self-tissues [1]. The Cyrex Array 12 was
specifically designed to detect these pathogen-associated
immune reactions that may contribute to autoimmune conditions.
What is the Cyrex Array 12?
The Array 12 - Pathogen-Associated Immune Reactivity Screen is a
specialized laboratory test developed by Cyrex Laboratories that
examines an individual's immune response to specific pathogens
known to increase susceptibility to autoimmune reactions [2]. It
measures antibodies against 32 different pathogens that may
lead to autoimmune reactivities through cross-reactivity and
molecular mimicry mechanisms.
Scientific Foundation and Development
The Array 12 was developed and published by Dr. Aristo Vojdani,
PhD, MSc, CLS, often referred to as "the father of functional
immunology." Dr. Vojdani has published extensive research on
molecular mimicry and environmental triggers of autoimmunity in
peer-reviewed journals between 2006 and 2024 [3]. His work has
demonstrated how various pathogens can trigger autoimmune
reactions through structural similarities between pathogen proteins
and human tissues.
The scientific concept behind the test is based on the principle
that when the immune system mounts a response against these
pathogens, the antibodies produced may cross-react with the
body's own tissues due to molecular similarities, potentially leading
to autoimmune reactions [4].
Pathogens Evaluated in Array 12
The Array 12 screens for immune reactivity to a comprehensive
range of pathogens including [5]:
Oral Pathogens
● Porphyromonas gingivalis
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