COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 559
markers in blood, potentially missing early immune dysfunction
occurring at mucosal surfaces. This diagnostic gap has led to the
development of more comprehensive mucosal immune
assessment tools, represented by Cyrex Array 14.
What is Array 14?
The Array 14 Mucosal Immune Reactivity Screen™ from Cyrex
Laboratories is a specialized saliva-based test that evaluates the
integrity and function of the mucosal immune system [5]. Unlike
conventional blood-based immune testing, Array 14 specifically
measures secretory IgA antibodies in saliva, providing crucial
information about immune activity at the body's primary defensive
barriers [6].
This innovative approach allows for the detection of mucosal
immune dysfunction before it manifests as systemic inflammation
or clinical symptoms [7]. By identifying early-stage immune
dysregulation at the mucosal level, Array 14 offers a window of
opportunity for intervention before more serious health conditions
develop.
What Array 14 Evaluates
Array 14 measures secretory IgA antibodies against 25 common
environmental antigens that typically enter through mucosal
surfaces. These antigens fall into several categories:
Food Proteins
Gluten/Wheat Proteins
Wheat gliadin, glutenin, and related peptides that are common
triggers of mucosal immune reactions
Dairy Proteins
Casein, whey, and other milk components that may disrupt
mucosal tolerance
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