COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 566
Chronic Fatigue and Systemic Inflammation
Patients with unexplained fatigue, widespread inflammation, or
generalized malaise that hasn't responded to conventional
approaches frequently have mucosal immune dysfunction as a
root cause [21]. Identifying and addressing specific mucosal
triggers can be transformative for these individuals.
Oral and Dental Issues
Those with recurrent oral ulcers, periodontal disease, or persistent
oral infections often have compromised oral mucosal immunity
[22]. Array 14 provides direct assessment of the oral immune
environment.
Conditions Where Array 14 is Especially Valuable
Array 14 is particularly useful for understanding potential mucosal
immune contributions to numerous chronic conditions:
Gastrointestinal Disorders
Irritable Bowel Syndrome (IBS)
Research indicates that up to 65% of IBS patients have altered
mucosal immune function [23]. Array 14 can identify specific
triggers contributing to symptoms.
Inflammatory Bowel Disease (IBD)
Mucosal immune dysregulation is central to conditions like Crohn's
disease and ulcerative colitis, with abnormal sIgA patterns often
preceding diagnosis [24].
Celiac Disease and Non-Celiac Gluten Sensitivity
Aberrant mucosal immune responses to gluten proteins are central
to these conditions [25]. Array 14 can differentiate between
various gluten peptides triggering reactions.
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