COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 567
Small Intestinal Bacterial Overgrowth (SIBO)
Altered mucosal immunity both contributes to and results from
dysbiotic gut conditions [26].
Autoimmune Conditions
Early-Stage or Suspected Autoimmunity
Mucosal immune dysfunction often precedes systemic
autoimmunity by months or years [27].
Autoimmune Thyroiditis
Research shows connections between gut mucosal immunity and
thyroid autoimmunity [28].
Rheumatoid Arthritis
Mucosal immune triggers, particularly from the oral cavity, have
been implicated in RA development [29].
Multiple Sclerosis
Gut mucosal barrier function and oral tolerance mechanisms
appear to play important roles in MS pathogenesis [30].
Respiratory Conditions
Chronic Sinusitis
Often involves dysfunction of the respiratory mucosal immune
barrier [31].
Asthma
Mucosal immune reactions can contribute to bronchial
hyperreactivity [32].
Recurrent Respiratory Infections
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