COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 589
resistant to digestion in human intestine. J Nutr.
1995;125(5):1238-1244.
[86] Campos-Rodríguez R, Godínez-Victoria M, Abarca-Rojano E,
et al. Stress modulates intestinal secretory immunoglobulin A. Front
Integr Neurosci. 2013;7:86.
[87] Vojdani A, Vojdani C. Immune reactivity to food coloring.
Altern Ther Health Med. 2015;21 Suppl 1:52-62.
[88] Kim KS, Hong SW, Han D, et al. Dietary antigens limit mucosal
immunity by inducing regulatory T cells in the small intestine.
Science. 2016;351(6275):858-863.
[89] Kharrazian D. The potential roles of bisphenol A (BPA)
pathogenesis in autoimmunity. Autoimmune Dis. 2014;2014:743616.
[90] Vojdani A, Vojdani E, Cooper E. Antibodies to myelin basic
protein, myelin oligodendrocytes peptides, ³-´-crystallin,
lymphocyte activation and cytokine production in patients with
multiple sclerosis. J Intern Med. 2003;254(4):363-374.
[91] Wells JM, Brummer RJ, Derrien M, et al. Homeostasis of the gut
barrier and potential biomarkers. Am J Physiol Gastrointest Liver
Physiol. 2017;312(3):G171-G193.
[92] Wildbaum G, Karin N. The role of cytokines and chemokines in
autoimmunity. Curr Opin Immunol. 2015;37:1-8.
Comprehensive Guide to Cyrex Array 20: Blood-Brain
Barrier Permeability Assessment, Biomarkers, and
Clinical Applications
Introduction: The Critical Blood-Brain Barrier Interface
The blood-brain barrier (BBB) represents a highly specialized
physiological boundary that meticulously regulates the exchange
of molecules and cells between the brain parenchyma and the
peripheral circulation [1]. Unlike capillaries in other organs, the
589
