COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 605
Indicators for Treatment Modification
Persistent or increasing antibody levels despite intervention
suggest the need to reassess triggers or modify treatment
approaches [181, 182]
Long-Term Monitoring Strategy
After initial resolution, periodic retesting (every 6-12 months) is
recommended for conditions with risk of recurrence [183, 184]
Future Directions: Emerging Research and Applications
The field of BBB assessment and treatment continues to evolve
rapidly, with several promising developments on the horizon:
Advanced Biomarker Panels
Integration of multiple biomarker classes including proteins,
microRNAs, and metabolites for more comprehensive BBB
assessment [185, 186]
Personalized Treatment Algorithms
AI-driven decision support systems to interpret complex biomarker
patterns and guide precision intervention [187, 188]
Targeted Drug Delivery Systems
Novel approaches to deliver neurotherapeutics across the BBB
using nanoparticles, exosomes, and receptor-mediated transport
[189, 190]
Regenerative Approaches
Stem cell therapies and growth factors to regenerate damaged
BBB components [191, 192]
Microbiome-Based Interventions
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