COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 609
[19] Iadecola C. The Neurovascular Unit Coming of Age: A
Journey through Neurovascular Coupling in Health and Disease.
Neuron. 2017;96(1):17-42.
[20] Kisler K, Nelson AR, Montagne A, Zlokovic BV. Cerebral blood
flow regulation and neurovascular dysfunction in Alzheimer
disease. Nat Rev Neurosci. 2017;18(7):419-434.
[21] Tietz S, Engelhardt B. Brain barriers: Crosstalk between
complex tight junctions and adherens junctions. J Cell Biol.
2015;209(4):493-506.
[22] Greene C, Hanley N, Campbell M. Claudin-5: gatekeeper of
neurological function. Fluids Barriers CNS. 2019;16(1):3.
[23] Furuse M, Hirase T, Itoh M, et al. Occludin: a novel integral
membrane protein localizing at tight junctions. J Cell Biol.
1993;123(6):1777-1788.
[24] Zihni C, Mills C, Matter K, Balda MS. Tight junctions: from simple
barriers to multifunctional molecular gates. Nat Rev Mol Cell Biol.
2016;17(9):564-580.
[25] Reijerkerk A, Kooij G, van der Pol SM, et al. The NR1 subunit of
NMDA receptor regulates monocyte transmigration through the
brain endothelial cell barrier. J Neurochem. 2010;113(2):447-453.
[26] Luissint AC, Artus C, Glacial F, Ganeshamoorthy K, Couraud
PO. Tight junctions at the blood brain barrier: physiological
architecture and disease-associated dysregulation. Fluids Barriers
CNS. 2012;9(1):23.
[27] Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM. The tight
junction protein ZO-1 establishes a link between the
transmembrane protein occludin and the actin cytoskeleton. J
Biol Chem. 1998;273(45):29745-29753.
609