COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 634
whether SIBO has triggered immune reactions that may
perpetuate symptoms even after bacterial reduction [19].
● Inflammatory Bowel Disease (IBD): For patients with Crohn's
disease or ulcerative colitis, identifying concurrent SIBO and
bacterial-driven immune reactions can be critical for
comprehensive management [20].
● Celiac Disease and Non-Celiac Gluten Sensitivity: These
conditions often involve bacterial dysbiosis and barrier
dysfunction beyond gluten reaction; Array 22 helps identify
these additional factors [21].
Systemic Conditions with Gut Connections
● Autoimmune Diseases: Growing evidence connects SIBO
and gut barrier dysfunction to the development or
exacerbation of various autoimmune conditions [22].
● Fibromyalgia and Chronic Fatigue Syndrome: These
conditions frequently involve gut dysfunction, with bacterial
translocation potentially contributing to systemic symptoms
[23].
● Neurological and Psychiatric Conditions: The gut-brain axis
can be significantly impacted by SIBO and bacterial
endotoxins, potentially contributing to neuroinflammation
[24].
● Skin Disorders: Conditions like rosacea, psoriasis, and eczema
show associations with SIBO and gut immune activation [25].
Comprehensive Treatment Approaches Based on Array 22 Results
The potential for reversing SIBO-related immune dysregulation
depends on several factors, including the antibody pattern,
chronicity, and extent of barrier damage. A comprehensive
approach typically includes:
Bacterial Reduction
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