COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 638
Modern stool testing provides valuable information about:
Large Intestinal Microbiome
Composition, diversity, and potential pathogens
Digestive Function
Enzyme production, fat malabsorption, and inflammation
Beneficial Bacteria Levels
Guiding probiotic recommendations
Array 22 focuses on small intestinal immune reactions, while stool
testing primarily reflects large intestinal status. Together, they
provide a more complete picture of gastrointestinal health [42].
Case Examples: Array 22 in Clinical Practice
Case 1: IBS with Predominant Bloating
A 35-year-old female presented with a 2-year history of progressive
bloating, abdominal distension, and constipation alternating with
loose stools. Previous evaluations included normal colonoscopy
and negative celiac testing.
Array 22 Results
● Elevated IgA and IgG antibodies to bacterial LPS
● Elevated IgA antibodies to occludin
● Normal IgM levels to all markers
This pattern suggested established mucosal immune activation
with early barrier compromise but not acute bacterial challenge.
Integration with Other Testing
● Positive lactulose breath test confirming SIBO
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