COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 666
● Medications affecting results: Corticosteroids,
immunosuppressants [62]
Analytical Methods
● Nephelometry: Most common method for quantitation [63]
● Turbidimetry: Alternative method with comparable accuracy
[64]
● Quality control standards: CAP/CLIA compliance
requirements [65]
Special Populations
Pediatric Considerations
● Age-specific reference ranges essential [66]
● Immunoglobulin levels increase progressively with age [67]
● Maternal antibody interference in early infancy [68]
Geriatric Populations
● Age-related immunosenescence affects Ig levels [69]
● Increased risk of immunodeficiency and autoimmunity [70]
● Medication interactions more common [71]
Pregnancy and Lactation
● Physiological changes in Ig levels during pregnancy [72]
● Transfer of maternal antibodies to fetus [73]
● Breastfeeding impact on infant immunoglobulin
development [74]
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