COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 687
Lyme Disease
Typically shows TH1/TH2 imbalances and regulatory T-cell
abnormalities [129, 130]
Chronic Viral Syndromes
May involve NK cell dysfunction, CD8+ T-cell abnormalities, and
regulatory disruption [131, 132]
Chronic Fatigue and Related Conditions
Conditions involving unexplained fatigue often demonstrate
characteristic immune patterns [133, 134]:
Chronic Fatigue Syndrome (CFS/ME)
Frequently shows NK cell dysfunction, TH2 shifts, and regulatory
abnormalities [135, 136]
Fibromyalgia
Often features altered cytokine patterns and NK cell functional
deficits [137, 138]
Post-Viral Fatigue
May involve persistent immune activation and regulatory
dysfunction [139, 140]
Allergic Conditions
Allergic disorders typically demonstrate TH2-weighted immune
responses [141, 142]:
Allergic Rhinitis
Usually shows TH2 dominance with elevated IL-4, IL-5, and IL-13
production [143, 144]
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