COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 762
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Expanded: Keystone Species and Their Clinical
Significance
Understanding the Keystone Concept in Microbial Ecology
The keystone species concept, originally developed in
macro-ecology, has profound implications when applied to the
human gut microbiome. In ecological terms, a keystone species
exerts disproportionately large influence relative to its abundance
[1]. In the gut microbiome, keystone species often:
● Orchestrate microbial community structure despite
representing a small percentage of total biomass [2]
● Create ecological niches that support broader community
diversity [3]
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