COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 769
● Antagonistic activity against pro-inflammatory bacteria [98]
● Generation of specialized lipid metabolites [99]
● Influence on circadian gene expression [100]
● Interaction with intestinal immune cells [101]
Clinical significance includes:
● Association with healthy weight maintenance [102]
● Correlation with reduced metabolic inflammation [103]
● Potential role in neurotransmitter production [104]
● Influence on gastrointestinal transit time [105]
● Protection against specific pathogens [106]
Alterations in Oscillibacter abundance may precede metabolic
disturbances [107].
Methanobrevibacter smithii
As the predominant archaeal species in the human gut, this
unique keystone:
● Removes hydrogen gas through methanogenesis [108]
● Increases energy harvest from dietary polysaccharides [109]
● Influences fermentation patterns of other microbes [110]
● Regulates intestinal transit time [111]
● Modifies redox potential in the gut environment [112]
● Affects SCFA production profiles [113]
● Enables syntrophic relationships between bacteria [114]
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