COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 804
A resilient microbiome typically correlates with improved clinical
outcomes and reduced symptom recurrence [27].
Understanding Functional Outputs
Rather than merely identifying which microbes are present,
advanced testing examines what these microorganisms are
actually doing [28]. Key functional analyses include:
Fermentation Patterns
Saccharolytic Fermentation
Saccharolytic fermentation involves the breakdown of complex
carbohydrates by beneficial bacteria [29]. This process:
● Produces beneficial short-chain fatty acids (SCFAs) [30]
● Supports gut barrier integrity [31]
● Provides energy for colonocytes [32]
● Regulates gut pH to discourage pathogen growth [33]
Low saccharolytic fermentation often indicates insufficient
prebiotic intake or depletion of beneficial fiber-fermenting
bacteria [34].
Proteolytic Fermentation
Proteolytic fermentation occurs when protein is broken down by
gut bacteria [35]. While normal in small amounts, excessive
proteolytic fermentation can produce problematic byproducts:
● Ammonia [36]
● Phenols [37]
● Sulfides [38]
● Various amines [39]
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