COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 805
These byproducts can be inflammatory and potentially toxic when
produced in excess [40]. High proteolytic fermentation may
indicate:
● Excessive protein consumption [41]
● Poor protein digestion in the upper GI tract [42]
● Dysbiotic shifts in microbial populations [43]
● Insufficient fiber intake to support saccharolytic fermentation
[44]
Gas Production Patterns
Microbial gas production provides additional insights into
functional patterns:
Methane Production
Methane-producing organisms (methanogens) can significantly
impact gut function by:
● Slowing intestinal transit time [45]
● Potentially contributing to constipation [46]
● Competing with beneficial acetate producers [47]
● Altering overall gut ecology [48]
Elevated methane production often correlates with specific
clinical presentations including constipation-predominant
conditions [49].
Hydrogen Sulfide Production
Hydrogen sulfide-producing bacteria convert dietary sulfur
compounds into hydrogen sulfide gas [50], which:
● Can be inflammatory to the intestinal lining in excess [51]
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