COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 809
Clinical Application: Beyond Identification to Intervention
Translating microbiome assessments into clinical interventions
requires systematic approaches:
Restoring Diversity
When alpha diversity is low, systematic restoration includes:
1. Identifying and removing diversity-limiting factors [92]
2. Providing broad-spectrum prebiotic support [93]
3. Introducing keystone organisms when appropriate [94]
4. Supporting ecosystem recovery through targeted
interventions [95]
Rebalancing Functional Outputs
Addressing functional imbalances involves:
1. Shifting fermentation patterns through specific fiber
interventions [96]
2. Enhancing digestive function to prevent proteolytic
fermentation [97]
3. Reducing inflammatory pathway activation [98]
4. Supporting beneficial metabolite production [99]
Ecological Recovery Phases
Recovery typically progresses through distinct phases:
1. Ecosystem preparation - removing disrupting factors and
providing basic support [100]
2. Reseeding - introducing beneficial organisms and stimulating
keystone species [101]
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