COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 840
Low levels indicate vitamin C deficiency.
Antioxidant Markers
Quinolinic acid, 5-OH-indoleacetic acid to quinolinic acid ratio
Interpretation
Imbalances suggest oxidative stress or insufficient antioxidant
capacity.
Clinical Significance of Vitamin Markers
These markers provide functional assessment of nutritional status:
B12 Status
Methylmalonic acid elevations indicate functional B12 deficiency.
This can occur despite normal serum B12 levels. Affects
neurological health, energy production, and methylation.
Folate Status
Formiminoglutamic acid elevations suggest folate deficiency.
Impacts methylation, DNA synthesis, and neurotransmitter
production.
B6 Status
Xanthurenic acid and kynurenic acid elevations indicate B6
deficiency. B6 is crucial for over 100 enzyme reactions, particularly
in neurotransmitter synthesis.
Antioxidant Status
Quinolinic acid elevations suggest inflammatory processes and
oxidative stress. Imbalanced ratios reveal compromised
antioxidant defense systems.
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