COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 847
[16] Patel KP, O'Brien TW, Subramony SH, et al. The spectrum of
pyruvate dehydrogenase complex deficiency: clinical,
biochemical and genetic features in 371 patients. Mol Genet
Metab. 2012;106(3):385-394.
[17] MacFabe DF. Enteric short-chain fatty acids: microbial
messengers of metabolism, mitochondria, and mind: implications
in autism spectrum disorders. Microb Ecol Health Dis.
2015;26:28177.
[18] Yap IKS, Angley M, Veselkov KA, et al. Urinary metabolic
phenotyping differentiates children with autism from their
unaffected siblings and age-matched controls. J Proteome Res.
2010;9(6):2996-3004.
[19] Ames BN, Elson-Schwab I, Silver EA. High-dose vitamin therapy
stimulates variant enzymes with decreased coenzyme binding
affinity (increased K(m)): relevance to genetic disease and
polymorphisms. Am J Clin Nutr. 2002;75(4):616-658.
[20] Parmeggiani B, Vargas CR. Oxidative stress in urea cycle
disorders: Findings from clinical and basic research. Clin Chim
Acta. 2018;477:121-126.
Genova Diagnostics: Company Overview and Testing
Panels
Company Background
Genova Diagnostics is one of the leading laboratories specializing
in functional and integrative medicine diagnostics.
Founded in 1986, Genova has decades of experience delivering
clinical insights into nutritional, gastrointestinal, hormonal,
metabolic, detoxification, and cardiovascular health [1].
Their tests are designed to identify underlying dysfunction
early4before it becomes chronic disease4allowing practitioners
to treat the root cause.
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