COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 852
● Estrogen metabolism pathways (2-OH, 4-OH, 16-OH
estrogens)
● Oxidative stress markers (e.g., 8-OHdG DNA oxidative
damage marker)
The DUTCH Test provides insight into hormone production,
hormone clearance through detoxification pathways, and
potential sources of hormone-driven inflammation or disease risk.
What Makes the DUTCH Test Different
● Dried Urine Collection:
Offers simple, non-invasive sample collection at four to five
points across the day for dynamic profiling.
● Comprehensive Hormone Mapping:
Measures parent hormones and their metabolites, revealing
both production and breakdown patterns.
● Circadian Rhythm Analysis:
Captures cortisol and melatonin curves, unlike single-point
blood draws.
● Estrogen Metabolism:
Assesses cancer-protective vs riskier estrogen pathways
(2-OH vs 4-OH and 16-OH metabolites).
● Cortisol Awakening Response (CAR):
Evaluates hypothalamic-pituitary-adrenal (HPA) axis
resilience and stress adaptation, critical for adrenal fatigue
and chronic stress cases.
● Oxidative Stress Detection:
Screens for early DNA oxidative damage which can increase
cancer and aging risks.
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