COMPENDIUM ON FUNCTIONAL MEDICINE - Flipbook - Page 892
CRP responses should be evaluated alongside clinical symptoms,
as decreasing values typically precede symptomatic
improvement [77, 78].
Metabolic Assessment: Hemoglobin A1c
Hemoglobin A1c (HbA1c) represents one of the most critical
markers for assessing glucose metabolism, insulin sensitivity, and
diabetic risk, providing a 2-3 month average of blood glucose
levels [79, 80].
Standard vs. Functional Interpretation
Conventional Reference Range
The standard clinical ranges for HbA1c are [81, 82]:
● Normal:
6.0%
Research shows that HbA1c levels above 5.4% correlate with
increasing cardiovascular and neurodegenerative risk,
highlighting the importance of earlier intervention [85, 86].
Clinical Significance and Beyond Diabetes
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